Enjoy Thanksgiving on Your GLP-1 Journey
- Nov 15, 2025
- 2 min read
Updated: Jul 21
Hey everyone — the holidays are the number-one "uh oh" moment patients ask us about, so here's the staff's collective wisdom, boiled down.
The good news first: your medication is actually on your side here. Semaglutide and Tirzepatide make you feel full fast on smaller amounts — which is exactly what Thanksgiving requires. The trick is working WITH that instead of against it.
Portions: half of what you'd normally take. Seriously. Fill half your plate with the veggie dishes, a quarter with turkey, a quarter with whatever carb you love most. You can always go back. Overeating on a GLP-1 leads to nausea and regret, not a food coma nap.
Protein first. Turkey breast is your friend — 25-30g of protein at the meal keeps you full longer and protects your muscle. Eat it before the stuffing, not after.
Watch the fat. This is the one that gets people. Fat slows stomach emptying, and your medication ALREADY slows stomach emptying. Gravy-drenched everything plus buttery mashed potatoes plus a GLP-1 is how you end up in the bathroom instead of watching the game. Roasted and grilled dishes beat casseroles.
Have a plan for Aunt Judy. You know the one — insists on filling your plate. Our patients handle it two ways: if people know about the medication, own it and let your progress speak. If you're keeping it private, small portions and "I'm pacing myself for pie" covers a lot.
Bring a dish you know you tolerate. Especially if fatty or sugary foods have started bothering you. You're guaranteed at least one safe option.
One more from experience across our 1,300+ patients: one meal never broke anyone's journey. Enjoy the day. Trust the process.
-Daryl
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